Ipamorelin / Epitalon / CJC-1295 No DAC Blend
Also known as: Ipamorelin + Epithalon + CJC-1295 No DAC Blend
A research blend combining the GH secretagogues Ipamorelin and CJC-1295 (No DAC) with the telomere-associated peptide Epitalon. It is studied for combined growth hormone support and longevity-oriented effects.
Last updated
Mechanism of Action
CJC-1295 (No DAC, modified GRF 1-29) activates the pituitary GHRH receptor to amplify GH pulse amplitude, while Ipamorelin selectively stimulates the GHS-R1a (ghrelin) receptor to produce a clean, additional GH pulse with minimal cortisol or prolactin effect, giving a synergistic increase in pulsatile GH and IGF-1. Epitalon (Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) studied for activation of telomerase and modulation of the pineal-gland melatonin axis, which is associated in research with longevity and circadian effects. The blend thus pairs two complementary GH secretagogue mechanisms with an independent telomere/pineal-targeted pathway.
- Half-life
- Mixed: Ipamorelin ~2 hours, CJC-1295 (No DAC) ~30 minutes, Epitalon very short (minutes) with proposed prolonged downstream effects
- Administration Routes
- subcutaneous
- Research Status
- Research Chemical
Reported Benefits
- Studied for synergistic endogenous GH release
- Investigated for telomerase activation via Epitalon
- Examined for improved sleep and circadian regulation
- Researched for recovery and lean mass support
- Studied for IGF-1 elevation through pituitary pathways
- Investigated for longevity-oriented anti-aging effects
Potential Side Effects
- Injection-site redness or transient swelling
- Mild water retention or tingling in extremities
- Transient flushing or lightheadedness
- Mild headache or fatigue
- Modest appetite increase
Common Dosing
Research-literature blends are studied at roughly 100-300 mcg of each GH secretagogue and 5-10 mg of Epitalon per cycle, typically administered daily or in short cycles. For research-use only; not personal medical advice.
The dosing information above is aggregated from research literature and anecdotal community reports for educational purposes only. It is not a recommendation, prescription, or medical advice. Peptides are sold as research chemicals only and are not intended for human use.
Contraindications
- Active malignancy or history of cancer
- Pregnancy or breastfeeding
- Known hypersensitivity to any component peptide
Sermorelin / Ipamorelin Blend
A widely studied research blend combining the GHRH analog Sermorelin with the highly selective ghrelin-receptor agonist Ipamorelin. It is examined for clean, synergistic growth hormone release with minimal off-target effects.
CJC-1295 (No DAC) / Ipamorelin / GHRP-2 Blend
This three-peptide blend pairs CJC-1295 without DAC (a GHRH analog) with two ghrelin-mimetic secretagogues, Ipamorelin and GHRP-2, to maximize a clean, synergistic growth hormone pulse. All components are unapproved research peptides.
N-Acetyl Epitalon Amidate
A modified, more stable form of the tetrapeptide Epitalon studied for telomerase activation and pineal-mediated circadian and longevity effects.