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Also known as: CJC-1295 & Ipamorelin & GHRP-2, Mod GRF 1-29 & Ipamorelin & GHRP-2, Mod GRF, Ipamorelin, GHRP-2
This three-peptide blend pairs CJC-1295 without DAC (a GHRH analog) with two ghrelin-mimetic secretagogues, Ipamorelin and GHRP-2, to maximize a clean, synergistic growth hormone pulse. All components are unapproved research peptides.
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CJC-1295 without DAC is a modified GHRH(1-29) analog that binds the pituitary GHRH receptor and increases the amplitude of growth-hormone pulses. Ipamorelin and GHRP-2 are both GHS-R1a (ghrelin-receptor) agonists that stimulate GH release and reduce somatostatin tone, but Ipamorelin is highly selective with minimal cortisol or prolactin effect, while GHRP-2 is more potent and adds appetite drive. Layering a GHRH analog with two secretagogues amplifies the synergistic GH pulse through complementary receptor signaling, with Ipamorelin offering a cleaner profile and GHRP-2 adding potency. The short-acting no-DAC backbone keeps GH and IGF-1 release pulsatile and physiologic.