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Also known as: CJC-1295, CJC-1295 DAC, Mod GRF 1-29
A long-acting growth hormone releasing hormone (GHRH) analog that stimulates the pituitary to produce more growth hormone. Often paired with a ghrelin mimetic for synergistic GH release.
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CJC-1295 is a modified GHRH (1-29) analog that binds the GHRH receptor on pituitary somatotrophs, stimulating endogenous growth hormone synthesis and release. The DAC (Drug Affinity Complex) version adds a lysine linker that binds serum albumin, dramatically extending half-life and prolonging GH and IGF-1 elevation. It preserves the natural pulsatile pattern of GH release rather than producing a constant supraphysiologic level.