How does this differ from the CJC-1295 / GHRP-2 blend?

It uses GHRP-6 instead of GHRP-2. GHRP-6 produces a similar synergistic GH pulse but with notably stronger appetite stimulation, which can be desirable for mass-gain research or unwanted otherwise.

Why is GHRP-6 known for hunger?

GHRP-6 strongly activates the ghrelin receptor in the hypothalamus, and ghrelin is the body's primary hunger signal, so a sharp increase in appetite typically follows administration.

Is this blend approved for human use?

No. Both peptides are unapproved research compounds sold strictly for laboratory study.

← All peptides

Growth Hormone Secretagogues

Research Chemical

CJC-1295 (No DAC) / GHRP-6 Blend

Also known as: CJC-1295 & GHRP-6, CJC-1295 No DAC + GHRP-6 Blend, Mod GRF 1-29 & GHRP-6

This blend combines CJC-1295 without DAC (Mod GRF 1-29), a GHRH analog, with GHRP-6, a ghrelin-mimetic secretagogue noted for strong appetite stimulation, to synergistically boost growth hormone release. Both are unapproved research peptides.

Mechanism of Action

CJC-1295 without DAC is a modified GHRH(1-29) analog that binds the pituitary GHRH receptor and increases the amplitude of endogenous growth-hormone pulses. GHRP-6 is a synthetic hexapeptide ghrelin mimetic that activates the GHS-R1a receptor to trigger GH release and reduce somatostatin inhibition, and it is the most potent of the GHRPs for stimulating appetite via central ghrelin signaling. Pairing a GHRH analog with GHRP-6 yields a synergistic GH pulse because the two receptor systems reinforce one another. The short half-life of the no-DAC form keeps GH and IGF-1 release pulsatile and physiologic.

Half-life: Short for both components: roughly 30 minutes for CJC-1295 no DAC and about 15-30 minutes for GHRP-6
Administration Routes: subcutaneous
Research Status: Research Chemical