Bromantane
Also known as: Bromantane
Bromantane is an adamantane-derived actoprotector with mild stimulant and anxiolytic properties, used clinically in Russia (as Ladasten) for asthenia and fatigue. It is a small-molecule research chemical, not a peptide, in most other markets. Note: Bromantane is a small-molecule actoprotector, not a peptide, though it is often catalogued with research peptides.
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Mechanism of Action
Bromantane is an atypical, indirectly acting dopaminergic agent that upregulates the biosynthetic enzymes tyrosine hydroxylase and aromatic L-amino acid decarboxylase, increasing dopamine synthesis in the hypothalamus and other regions. This gradual enhancement of dopaminergic and, secondarily, serotonergic neurotransmission underlies its combined stimulant and anxiolytic ('actoprotector') profile, improving endurance and stress resistance without the sharp peaks of classical psychostimulants. It also exhibits mild immunostimulant activity and supports physical work capacity under hypoxic or high-load conditions.
- Half-life
- Approximately 10-11 hours in humans
- Administration Routes
- oral
- Research Status
- Research Chemical
Reported Benefits
- Reduces fatigue and asthenia in clinical use
- Combined mild stimulant and anxiolytic effects
- Improves physical work capacity and endurance
- Supports stress resistance (actoprotector activity)
- Mild immunostimulant properties
Potential Side Effects
- Insomnia or sleep disruption if taken late
- Restlessness or overstimulation at higher amounts
- Headache
- Banned in competitive sport (WADA prohibited substance)
Common Dosing
For research use only and not medical advice: Russian clinical literature for Ladasten describes oral courses in the range of roughly 50-100 mg per day for limited periods. This is provided as historical reference, not personal dosing guidance.
The dosing information above is aggregated from research literature and anecdotal community reports for educational purposes only. It is not a recommendation, prescription, or medical advice. Peptides are sold as research chemicals only and are not intended for human use.
Contraindications
- Use by competitive athletes subject to anti-doping rules
- Psychiatric conditions worsened by dopaminergic stimulation
- Pregnancy or breastfeeding
- Concurrent strong dopaminergic or stimulant drugs
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Noopept
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[Ladasten, the new drug with psychostimulant and anxiolytic actions in treatment of neurasthenia (results of the comparative clinical study with placebo)]
2009
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[Treatment of asthenic disorders in patients with psychoautonomic syndrome: results of a multicenter study on efficacy and safety of ladasten]
2010
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[Role of the brain dopaminergic and serotoninergic systems in psychopharmacological effects of ladasten and sydnocarb]
2010
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The pharmacology of actoprotectors: practical application for improvement of mental and physical performance
2012