How does Vialox smooth wrinkles?

It competitively blocks acetylcholine receptors at the skin's neuromuscular junction, reducing local muscle contraction so dynamic expression lines appear softer.

Is Vialox injected like a neurotoxin?

No. It is a topical cosmetic peptide applied to the skin surface, not an injectable, and its effect is milder and reversible.

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Collagen & Skin

Healing & Recovery

Research Chemical

Vialox (Pentapeptide-3V)

Also known as: Vialox, Pentapeptide-3V, Pentapeptide-3

Vialox is a topical pentapeptide marketed as a needle-free muscle-relaxing cosmetic ingredient. It is studied for softening expression lines by reducing local muscle contraction at the skin surface.

Mechanism of Action

Vialox (pentapeptide-3) acts as a competitive antagonist at the postsynaptic acetylcholine receptor of the neuromuscular junction in the skin. By blocking acetylcholine binding it reduces muscle fiber contraction in the manner of a curare-like, topically applied agent. The resulting decrease in repeated micro-contractions is intended to smooth dynamic expression lines. Its activity is local and reversible, relying on continued application for a sustained cosmetic effect.

Half-life: Not systemically relevant; acts locally in topical use
Administration Routes: topical
Research Status: Research Chemical