Thymalin
Also known as: Thymalin
A thymus-derived peptide preparation studied in Russian research for immune restoration and age-related immune support, often paired with Epitalon in longevity protocols.
Last updated
Mechanism of Action
Thymalin is a polypeptide fraction extracted from the thymus gland that is reported to regulate T-lymphocyte differentiation and restore balance between immune cell populations. It is thought to modulate the neuroendocrine-immune axis and support thymic function, which declines with age. Russian studies describe normalization of immune markers and, in combination with Epitalon, effects on age-related morbidity and mortality.
- Half-life
- Short; peptide fraction acting over days
- Administration Routes
- intramuscular, subcutaneous
- Research Status
- Preclinical
Reported Benefits
- Supports T-cell differentiation and immune balance
- May restore age-related immune decline
- Studied for longevity, especially with Epitalon
- Reported reductions in age-related morbidity in Russian trials
- Modulates the neuroendocrine-immune axis
Potential Side Effects
- Generally well tolerated in available studies
- Injection-site reactions
- Allergic reaction possible (animal-derived fractions)
- Limited Western clinical validation
Common Dosing
Russian research references ~5-10 mg per day in short courses of 5-10 days, repeated periodically. Educational range only, not advice.
The dosing information above is aggregated from research literature and anecdotal community reports for educational purposes only. It is not a recommendation, prescription, or medical advice. Peptides are sold as research chemicals only and are not intended for human use.
Contraindications
- Known hypersensitivity to thymic preparations
- Pregnancy or breastfeeding
- Autoimmune conditions (consult research literature)
Epitalon
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the pineal peptide epithalamin, studied for telomerase activation, circadian regulation, and longevity in animal and limited human research.
Thymosin Alpha-1
A thymus-derived immunomodulating peptide approved in many countries (as Zadaxin) for hepatitis and as an immune adjuvant. Studied for restoring and balancing immune function.
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