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Also known as: TB-500, Thymosin Beta-4, TB-4
A synthetic version of the active region of Thymosin Beta-4, a naturally occurring peptide that regulates cell migration and tissue repair. Researched for recovery, flexibility, and wound healing.
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TB-500 corresponds to the actin-binding domain of Thymosin Beta-4 and regulates actin polymerization, which governs cell migration, proliferation, and differentiation. By sequestering G-actin and promoting cytoskeletal remodeling, it enables cells such as endothelial and stem cells to migrate to sites of injury. It also upregulates genes associated with angiogenesis and downregulates inflammatory cytokines in preclinical models.