Is SLU-PP-332 a peptide?

No. It is a synthetic small molecule that activates estrogen-related receptors, not a peptide. It is grouped with metabolic research compounds because of its exercise-mimetic effects.

What is an exercise mimetic?

An exercise mimetic is a compound that reproduces some molecular adaptations of physical training, such as increased mitochondrial capacity and fat oxidation, without the exercise itself. SLU-PP-332 produces this profile in animal studies.

Has SLU-PP-332 been tested in humans?

No. The evidence is preclinical, based on rodent models, and there is no established human safety or dosing data. It is sold for research purposes only.

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Weight & Metabolic

Preclinical

SLU-PP-332

Also known as: SLU-PP-332

SLU-PP-332 is a synthetic small-molecule pan-agonist of the estrogen-related receptors (ERRs) studied as an exercise mimetic that increases fat oxidation and endurance in animal models. It is a research chemical, not a peptide.

Mechanism of Action

SLU-PP-332 is a small-molecule agonist of the estrogen-related receptors ERRalpha, ERRbeta, and ERRgamma, orphan nuclear receptors that govern mitochondrial biogenesis and oxidative metabolism. By activating ERRs, the compound up-regulates genes in the fatty-acid oxidation and oxidative phosphorylation programs, shifting cellular fuel use toward fat and increasing mitochondrial capacity in skeletal muscle. In rodent studies this drives a phenotype resembling endurance exercise, with greater running capacity, increased energy expenditure, and resistance to diet-induced obesity, hence the description as an exercise mimetic.

Half-life: Short in rodents (on the order of hours); human pharmacokinetics not established
Administration Routes: subcutaneous, oral
Research Status: Preclinical

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Available from vendors

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Peptide ClubSLU-PP-332 · from $38.99

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Research Vendors

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