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Also known as: Selank
A synthetic analog of the immunomodulatory peptide tuftsin developed in Russia for anxiety reduction and cognitive support without the sedation or dependence of benzodiazepines.
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Selank is a heptapeptide derived from tuftsin that modulates the balance of monoamines and increases expression of BDNF in the hippocampus. It influences GABAergic and serotonergic signaling, producing anxiolytic effects without sedation, and stabilizes enkephalins by inhibiting their breakdown. It also has documented immunomodulatory activity, reflecting its tuftsin origin.