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Also known as: Epitalon, Epithalon, Epithalamin
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the pineal peptide epithalamin, studied for telomerase activation, circadian regulation, and longevity in animal and limited human research.
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Epitalon is a synthetic tetrapeptide modeled on the pineal-gland peptide epithalamin that has been reported to activate telomerase, the enzyme that maintains telomere length. Preclinical work suggests it normalizes melatonin and circadian rhythm, modulates the hypothalamic-pituitary axis, and exerts antioxidant effects. Russian studies report effects on lifespan and age-related markers, though mechanisms in humans remain incompletely defined.