Loading peptide…
PeptideChat is for educational and research purposes only. Nothing on this site constitutes medical advice. Peptides are sold as research chemicals only and are not intended for human use. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. PeptideChat is an independent educational resource — not a pharmacy, compounding, or 503A/503B outsourcing facility — and does not sell products or provide medical advice.
Also known as: Dihexa, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
A small-molecule angiotensin IV analog studied for potent procognitive and synaptogenic effects, reported in preclinical work to be orders of magnitude more potent than BDNF at forming synapses.
Sign in to rate this peptide.
Dihexa is an orally active, blood-brain-barrier-penetrant angiotensin IV analog that acts on the hepatocyte growth factor (HGF)/c-Met receptor system. By potentiating HGF/c-Met signaling, it promotes synaptogenesis and dendritic spine formation in the hippocampus. Preclinical research reports it facilitates new functional synapse formation at extremely low concentrations, underlying its interest for memory and neurodegenerative models.