Cardiogen
Also known as: Cardiogen
Cardiogen is a short synthetic peptide (Ala-Glu-Asp-Arg) studied as a cardiovascular bioregulator intended to support heart and vascular tissue. It belongs to the Khavinson family of short peptide bioregulators.
Last updated
Mechanism of Action
Cardiogen is a tetrapeptide (AEDR) proposed to act as a tissue-specific bioregulator by penetrating cells and binding regulatory regions of DNA to modulate gene expression in cardiomyocytes and vascular tissue. It is thought to normalize protein synthesis associated with myocardial cell maintenance and to support endothelial function. By promoting homeostatic gene expression in cardiac tissue, it is studied for slowing age-related decline in heart muscle function.
- Half-life
- Short (minutes), consistent with rapid clearance of small tetrapeptides
- Administration Routes
- subcutaneous, intramuscular
- Research Status
- Research Chemical
Reported Benefits
- Studied for support of cardiac muscle and vascular tissue function
- Proposed to aid age-related cardiovascular maintenance
- May support endothelial and microvascular health
- Short peptide with generally low immunogenicity
- Investigated as part of geroprotective bioregulator protocols
Potential Side Effects
- Sparse human safety data
- Possible injection-site irritation
- Potential allergic or hypersensitivity reactions
- Unknown long-term cardiovascular effects
Common Dosing
For research use only and not medical advice: bioregulator references describe courses of roughly 100-200 mcg daily via subcutaneous or intramuscular injection across 10-20 day cycles; no validated clinical dosing exists.
The dosing information above is aggregated from research literature and anecdotal community reports for educational purposes only. It is not a recommendation, prescription, or medical advice. Peptides are sold as research chemicals only and are not intended for human use.
Contraindications
- Pregnancy and breastfeeding
- Known peptide hypersensitivity
- Acute or unstable cardiovascular disease without medical oversight
Vesugen
Vesugen is a short tripeptide bioregulator studied for support of the vascular system and blood-vessel wall integrity. It is part of the Khavinson peptide family aimed at tissue-specific regulation.
Cartalax
Cartalax is a short synthetic peptide (Ala-Glu-Asp-Gly) studied as a bioregulator for cartilage and connective tissue. It is part of the Khavinson short peptide bioregulator family.
Epitalon
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the pineal peptide epithalamin, studied for telomerase activation, circadian regulation, and longevity in animal and limited human research.
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Tetrapeptide H-Ala-Glu-Asp-Arg-OH stimulates expression of cytoskeletal and nuclear matrix proteins
2012
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[The effect of the amino acids and cardiogen on the development of myocard tissue culture from young and old rats]
2009
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Tumor-modifying effect of cardiogen peptide on M-1 sarcoma in senescent rats
2009
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Senescence-Associated Secretory Phenotype of Cardiovascular System Cells and Inflammaging: Perspectives of Peptide Regulation
2022