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Also known as: ABP-7
ABP-7 is a research peptide marketed as an analog within the alpha-MSH / melanocortin family, studied for its potential anti-inflammatory and tissue-protective signaling.
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ABP-7 is described as a melanocortin-pathway agonist that acts on melanocortin receptors (notably MC1R and MC3R) expressed on immune and tissue cells. Activation of these G-protein-coupled receptors raises intracellular cAMP and downregulates pro-inflammatory transcription factors such as NF-kB, reducing cytokine output. By biasing macrophages toward a resolving phenotype, melanocortin agonists in this class are studied for resolution of inflammation rather than simple suppression.